BDBM50247603 2-[1'-(4-Chlorophenyl)-3'-thienyl-2'-propenylidene]hydrazine-3-methyl)-4(3H)-quinazolinone::CHEMBL491469

SMILES Cn1c(N=NC(=CCc2cccs2)c2ccc(Cl)cc2)nc2ccccc2c1=O

InChI Key InChIKey=DBXOMBIWWMARLL-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50247603   

TargetAmine oxidase [flavin-containing] A(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247603(2-[1'-(4-Chlorophenyl)-3'-thienyl-2'-propenylidene...)
Affinity DataIC50: 2.81E+4nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by residual activity plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247603(2-[1'-(4-Chlorophenyl)-3'-thienyl-2'-propenylidene...)
Affinity DataKi:  2.82E+4nMAssay Description:Inhibition of MAO-A in rat liver homogenate after 60 mins by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247603(2-[1'-(4-Chlorophenyl)-3'-thienyl-2'-propenylidene...)
Affinity DataKi:  6.91E+4nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50247603(2-[1'-(4-Chlorophenyl)-3'-thienyl-2'-propenylidene...)
Affinity DataIC50: 4.16E+5nMAssay Description:Inhibition of MAO-B in rat liver homogenate after 60 mins by residual activity plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed