BDBM50247839 CHEMBL447612::methyl 3-(5-chloro-3-oxoisothiazol-2(3H)-yl)propanoate

SMILES COC(=O)CCn1sc(Cl)cc1=O

InChI Key InChIKey=IUQRHPPJEZXEGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247839   

TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50247839(methyl 3-(5-chloro-3-oxoisothiazol-2(3H)-yl)propan...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant histone acetyltransferase PCAF assessed as CoA-SH activity preincubated for 15 mins by CPM fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50247839(methyl 3-(5-chloro-3-oxoisothiazol-2(3H)-yl)propan...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant HAT PCAFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed