BDBM50247959 4-(butylthio)-2-(trifluoromethyl)benzonitrile::CHEMBL462665

SMILES CCCCSc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=FQVZVSZPULBOJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247959   

TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247959(4-(butylthio)-2-(trifluoromethyl)benzonitrile | CH...)
Affinity DataIC50: 49nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50247959(4-(butylthio)-2-(trifluoromethyl)benzonitrile | CH...)
Affinity DataIC50: 838nMAssay Description:Antagonist activity at human androgen receptor expressed in human MDA-MB453 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed