BDBM50248116 CHEMBL461991::N4-(4-(benzo[d]thiazol-2-yl)phenyl)-N2-(5-methyl-1H-pyrazol-3-yl)pyridine-2,4-diamine

SMILES Cc1cc(Nc2cc(Nc3ccc(-c4nc5ccccc5s4)cc3)ccn2)[nH]n1

InChI Key InChIKey=MVXAWROAJALYHX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50248116   

TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248116BDBM50248116(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-N2-(5-methyl-1...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248116BDBM50248116(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-N2-(5-methyl-1...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248116BDBM50248116(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-N2-(5-methyl-1...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of VEGFR3 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248116BDBM50248116(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-N2-(5-methyl-1...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of VEGFR2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248116BDBM50248116(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-N2-(5-methyl-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248116BDBM50248116(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-N2-(5-methyl-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ErbB2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248116BDBM50248116(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-N2-(5-methyl-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed