BDBM50248150 CHEMBL462338::N-(4-(benzo[d]thiazol-2-yl)phenyl)-2-methoxy-7H-pyrrolo[2,3-d]pyrimidin-4-amine

SMILES COc1nc(Nc2ccc(-c3nc4ccccc4s3)cc2)c2cc[nH]c2n1

InChI Key InChIKey=OJBMEBMIUCBAAE-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50248150   

LigandChemical structure of BindingDB Monomer ID 50248150BDBM50248150(N-(4-(benzo[d]thiazol-2-yl)phenyl)-2-methoxy-7H-py...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of IGF1R by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248150BDBM50248150(N-(4-(benzo[d]thiazol-2-yl)phenyl)-2-methoxy-7H-py...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Src by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248150BDBM50248150(N-(4-(benzo[d]thiazol-2-yl)phenyl)-2-methoxy-7H-py...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248150BDBM50248150(N-(4-(benzo[d]thiazol-2-yl)phenyl)-2-methoxy-7H-py...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of TIE2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248150BDBM50248150(N-(4-(benzo[d]thiazol-2-yl)phenyl)-2-methoxy-7H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR3 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248150BDBM50248150(N-(4-(benzo[d]thiazol-2-yl)phenyl)-2-methoxy-7H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248150BDBM50248150(N-(4-(benzo[d]thiazol-2-yl)phenyl)-2-methoxy-7H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248150BDBM50248150(N-(4-(benzo[d]thiazol-2-yl)phenyl)-2-methoxy-7H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ErbB2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248150BDBM50248150(N-(4-(benzo[d]thiazol-2-yl)phenyl)-2-methoxy-7H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248150BDBM50248150(N-(4-(benzo[d]thiazol-2-yl)phenyl)-2-methoxy-7H-py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed