BDBM50248181 4-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzyl)-1-phenyl-1H-pyrrole-3-carboxylic acid::CHEMBL514328

SMILES Cc1oc(nc1CCOc1ccc(Cc2cn(cc2C(O)=O)-c2ccccc2)cc1)-c1ccccc1

InChI Key InChIKey=FIMKQDMLWGFYLN-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248181   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50248181(4-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataEC50:  660nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in HEK293 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50248181(4-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataIC50: 890nMAssay Description:Binding affinity to PPARalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50248181(4-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataIC50: 890nMAssay Description:Binding affinity to PPARgamma by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50248181(4-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzy...)
Affinity DataEC50:  4.20E+3nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in HEK293 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed