BDBM50248257 (E)-N-hydroxy-3-(1-(3-hydroxypropyl)-1H-benzo[d]imidazol-5-yl)acrylamide::CHEMBL507008::US10201527, Compound 47::US10736881, Compound 47

SMILES OCCCn1cnc2cc(\C=C\C(=O)NO)ccc12

InChI Key InChIKey=OUFDENCCUPKHBQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50248257   

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248257((E)-N-hydroxy-3-(1-(3-hydroxypropyl)-1H-benzo[d]im...)
Affinity DataIC50: 1.09E+3nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248257((E)-N-hydroxy-3-(1-(3-hydroxypropyl)-1H-benzo[d]im...)
Affinity DataIC50: 1.09E+3nMAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Mei Pharma

US Patent
LigandPNGBDBM50248257((E)-N-hydroxy-3-(1-(3-hydroxypropyl)-1H-benzo[d]im...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant HDAC1 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed