BDBM50248348 2-(benzo[d]thiazol-2-yl)-5-(6,7-dimethoxyquinazolin-4-ylamino)phenol::CHEMBL473351

SMILES COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)c(O)c3)c2cc1OC

InChI Key InChIKey=MPXQJBIEYPHEBG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50248348   

TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248348BDBM50248348(2-(benzo[d]thiazol-2-yl)-5-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248348BDBM50248348(2-(benzo[d]thiazol-2-yl)-5-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248348BDBM50248348(2-(benzo[d]thiazol-2-yl)-5-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of VEGFR2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248348BDBM50248348(2-(benzo[d]thiazol-2-yl)-5-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EphB4 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248348BDBM50248348(2-(benzo[d]thiazol-2-yl)-5-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1R by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248348BDBM50248348(2-(benzo[d]thiazol-2-yl)-5-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Src by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248348BDBM50248348(2-(benzo[d]thiazol-2-yl)-5-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248348BDBM50248348(2-(benzo[d]thiazol-2-yl)-5-(6,7-dimethoxyquinazoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed