BDBM50248351 CHEMBL473761::N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-N2-(5-methyl-1H-pyrazol-3-yl)quinazoline-2,4-diamine

SMILES COc1cc2nc(Nc3cc(C)n[nH]3)nc(Nc3ccc(-c4nc5ccccc5s4)cc3)c2cc1OC

InChI Key InChIKey=SAMQZLCXVPNZIG-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50248351   

LigandChemical structure of BindingDB Monomer ID 50248351BDBM50248351(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of IGF1R by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248351BDBM50248351(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of insulin receptor by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248351BDBM50248351(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Src by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248351BDBM50248351(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of EphB4 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248351BDBM50248351(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Aurora A by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248351BDBM50248351(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TIE2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50248351BDBM50248351(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248351BDBM50248351(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
4Sc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50248351BDBM50248351(N4-(4-(benzo[d]thiazol-2-yl)phenyl)-6,7-dimethoxy-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora B by virtual HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed