BDBM50248505 3-chloro-4-(o-tolyloxy)benzonitrile::CHEMBL490955

SMILES Cc1ccccc1Oc1ccc(cc1Cl)C#N

InChI Key InChIKey=LMZHFUQMQDTSFO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248505   

TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248505(3-chloro-4-(o-tolyloxy)benzonitrile | CHEMBL490955)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human androgen receptor expressed in human MDA-MB-231 cells assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248505(3-chloro-4-(o-tolyloxy)benzonitrile | CHEMBL490955)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human androgen receptor expressed in human MDA-MB453 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248505(3-chloro-4-(o-tolyloxy)benzonitrile | CHEMBL490955)
Affinity DataIC50: 64nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248505(3-chloro-4-(o-tolyloxy)benzonitrile | CHEMBL490955)
Affinity DataIC50: 64nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in insect Sf9 cell systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed