BDBM50248506 3-chloro-4-(o-tolylthio)benzonitrile::CHEMBL490956

SMILES Cc1ccccc1Sc1ccc(cc1Cl)C#N

InChI Key InChIKey=XNDBEERQWNGTKH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248506   

TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248506(3-chloro-4-(o-tolylthio)benzonitrile | CHEMBL49095...)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248506(3-chloro-4-(o-tolylthio)benzonitrile | CHEMBL49095...)
Affinity DataIC50: 43nMAssay Description:Binding affinity to human Androgen receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248506(3-chloro-4-(o-tolylthio)benzonitrile | CHEMBL49095...)
Affinity DataIC50: 78nMAssay Description:Antagonist activity at Androgen receptor in human MDA-kb2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50248506(3-chloro-4-(o-tolylthio)benzonitrile | CHEMBL49095...)
Affinity DataIC50: 78nMAssay Description:Antagonist activity at human androgen receptor expressed in human MDA-MB453 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed