BDBM50249002 CHEMBL4096707

SMILES CC1(C)Oc2cc(ccc2-c2nc([nH]c12)-c1c(Cl)cncc1Cl)C#Cc1cc(ccc1Cl)C(F)(F)F

InChI Key InChIKey=XEOXRXXKYLNMCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249002   

TargetProstaglandin E synthase(Human)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249002(CHEMBL4096707)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human mPGES-1 expressed in CHO cells assessed as reduction in PGE2 formation using PGH2 a substrate preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed