BDBM50249022 CHEMBL4076684

SMILES CC1(C)Oc2cc(ccc2-c2nc([nH]c12)-c1c(Cl)cncc1Cl)C#Cc1ccccc1C(F)(F)F

InChI Key InChIKey=AGQJYDLOHQJVIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249022   

TargetProstaglandin E synthase(Human)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249022(CHEMBL4076684)
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant human mPGES-1 expressed in CHO cells assessed as reduction in PGE2 formation using PGH2 a substrate preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2019
Entry Details Article
PubMed