BDBM50249080 CHEMBL474575::N-(3-chloro-4-hydroxynaphthalen-1-yl)-2,4-dimethylbenzenesulfonamide

SMILES Cc1ccc(c(C)c1)S(=O)(=O)Nc1cc(Cl)c(O)c2ccccc12

InChI Key InChIKey=HUKBNTCGEZRIAK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249080   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50249080(N-(3-chloro-4-hydroxynaphthalen-1-yl)-2,4-dimethyl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50249080(N-(3-chloro-4-hydroxynaphthalen-1-yl)-2,4-dimethyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed