BDBM50249110 4-(4-butoxy-3-methylbenzoyl)-3-hydroxy-1-(pyridin-3-ylmethyl)-5-p-tolyl-1H-pyrrol-2(5H)-one::CHEMBL514305

SMILES CCCCOc1ccc(cc1C)C(=O)C1C(N(Cc2cccnc2)C(=O)C1=O)c1ccc(C)cc1

InChI Key InChIKey=FPQLKVUKYICRSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249110   

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50249110(4-(4-butoxy-3-methylbenzoyl)-3-hydroxy-1-(pyridin-...)
Affinity DataIC50: 8.48E+3nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50249110(4-(4-butoxy-3-methylbenzoyl)-3-hydroxy-1-(pyridin-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed