BDBM50249237 2-(4-chlorophenyl)-4-(5-methyl-1H-pyrazol-3-ylamino)phthalazin-1(2H)-one::CHEMBL452355

SMILES Cc1cc(Nc2nn(-c3ccc(Cl)cc3)c(=O)c3ccccc23)[nH]n1

InChI Key InChIKey=DFYXAPVQNGLJHI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249237   

TargetAurora kinase A(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50249237(2-(4-chlorophenyl)-4-(5-methyl-1H-pyrazol-3-ylamin...)
Affinity DataIC50: 93nMAssay Description:Inhibition of Aurora A by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50249237(2-(4-chlorophenyl)-4-(5-methyl-1H-pyrazol-3-ylamin...)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of recombinant SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50249237(2-(4-chlorophenyl)-4-(5-methyl-1H-pyrazol-3-ylamin...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Aurora B by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed