BDBM50249395 (R)-2-cyclohexyl-2-((3S,4S)-3-phenyl-4-((4-(3-phenylisoxazol-5-yl)piperidin-1-yl)methyl)pyrrolidin-1-yl)acetic acid::CHEMBL511806

SMILES OC(=O)[C@@H](C1CCCCC1)N1C[C@H](CN2CCC(CC2)c2cc(no2)-c2ccccc2)[C@H](C1)c1ccccc1

InChI Key InChIKey=KMJXNUMOUQQANC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249395   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249395((R)-2-cyclohexyl-2-((3S,4S)-3-phenyl-4-((4-(3-phen...)
Affinity DataIC50: 18nMAssay Description:Inhibitory concentration against C-C chemokine receptor type 5 using [125I]-MIP-1 alpha as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50249395((R)-2-cyclohexyl-2-((3S,4S)-3-phenyl-4-((4-(3-phen...)
Affinity DataIC50: 18.1nMAssay Description:Displacement of [125I]MIP1alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed