BDBM50249438 CHEMBL4099560

SMILES Cc1nnc2sc(C(=O)NCc3ccc(Br)cc3)c(N)c2c1C

InChI Key InChIKey=XJWCAEZVUWIXSC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249438   

TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50249438(CHEMBL4099560)
Affinity DataEC50:  182nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 assessed as increase in acetylcholine-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2019
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50249438(CHEMBL4099560)
Affinity DataEC50:  187nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells coexpressing Gqi5 assessed as increase in acetylcholine-induced calcium mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2019
Entry Details Article
PubMed