BDBM50249509 5-((1R,2S)-2-Aminocyclohexylamino)-7-(3,5-dimethoxyphenylamino)-2-phenylimidazo[1,2-c]pyrimidine-8-carboxamide::CHEMBL511977

SMILES COc1cc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)n3cc(nc3c2C(N)=O)-c2ccccc2)cc(OC)c1

InChI Key InChIKey=UCDYGVBDFHZXEE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249509   

TargetTyrosine-protein kinase SYK(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249509(5-((1R,2S)-2-Aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50: 380nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249509(5-((1R,2S)-2-Aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ZAP-70(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249509(5-((1R,2S)-2-Aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed