BDBM50249526 2-(2,4-dibromophenoxy)-N-(3-(1-hydroxyethyl)phenyl)propanamide::CHEMBL449922

SMILES CC(O)c1cccc(NC(=O)C(C)Oc2ccc(Br)cc2Br)c1

InChI Key InChIKey=GKJWYULRCHAYTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249526   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50249526(2-(2,4-dibromophenoxy)-N-(3-(1-hydroxyethyl)phenyl...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50249526(2-(2,4-dibromophenoxy)-N-(3-(1-hydroxyethyl)phenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assay in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed