BDBM50249738 2-(4,4-bis(4-fluorophenyl)-4,5-dihydro-1H-imidazol-2-yl)pyrazine::CHEMBL490937
SMILES Fc1ccc(cc1)C1(CNC(=N1)c1cnccn1)c1ccc(F)cc1
InChI Key InChIKey=MGAGGIYVXPYGLM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50249738
Affinity DataKi: 4.30nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in mouse LMtk- cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Displacement of [35S]N-[(4R)-1'-[(2R)-6-cyano-1,2,3,4-tetrahydro-2-naphthyl]-3,4-dihydro-4-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]6-yl]methanesu...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at human recombinant neuropeptide Y5 receptor expressed in thymidine kinase-deficient mouse LM cells assessed as inhibition of ne...More data for this Ligand-Target Pair