BDBM50249856 12-(Dimethylamino)-2,3,6,7-tetrahydro-9-(N-piperidyl-2-thienyl-5-thiocarboxamido)-1H,5H-telluroxantheno[2,3,4-ij]quinolizin-14-ium Hexafluorophosphate::CHEMBL508580

SMILES [#6]\[#7+](-[#6])=[#6]-1\[#6]=[#6]-[#6]-2=[#6](-c3ccc(s3)-[#6](=S)-[#7]-3-[#6]-[#6]-[#6]-[#6]-[#6]-3)-c3cc4-[#6]-[#6]-[#6]-[#7]-5-[#6]-[#6]-[#6]-c(c3[Te][#6]-2=[#6]-1)c4-5

InChI Key InChIKey=RJTNUJBISGLHKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249856   

TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50249856(12-(Dimethylamino)-2,3,6,7-tetrahydro-9-(N-piperid...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human MDR1 expressed in MDCK2 cells assessed as enhancement of Calcein-AM uptake treated 30 mins before Calcein-AM challenge measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed