BDBM50250009 CHEMBL4096137::US11208411, Compound FUR

SMILES Nc1ncnc2n(CC3CCNCC3)nc(Cc3cccc(Cl)c3)c12

InChI Key InChIKey=GPDICWJXBQZXCY-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50250009   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of California

Curated by ChEMBL
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50:  15nMAssay Description:Inhibition of C-terminal His-tagged full length Toxoplasma gondii CDPK1 expressed in Escherichia coli BL21 (DE3) using syntide-2 as substrate pre-inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Src kinase domain (254 to 536 residues) expressed in Escherichia coli BL21 (DE3) using abltide as substrate pre-incubated for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCAM kinase, CDPK family TgCDPK1(Toxoplasma gondii (strain ATCC 50861 / VEG))
The Regents of The University of California

US Patent
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50:  14.5nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50: >1.00E+4nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCAM kinase, CDPK family TgCDPK1(Toxoplasma gondii (strain ATCC 50861 / VEG))
The Regents of The University of California

US Patent
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50:  13.5nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50: >1.00E+4nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCAM kinase, CDPK family TgCDPK1(Toxoplasma gondii (strain ATCC 50861 / VEG))
The Regents of The University of California

US Patent
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50:  325nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50: >1.00E+4nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCAM kinase, CDPK family TgCDPK1(Toxoplasma gondii (strain ATCC 50861 / VEG))
The Regents of The University of California

US Patent
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50:  325nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50: >1.00E+4nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCAM kinase, CDPK family TgCDPK1(Toxoplasma gondii (strain ATCC 50861 / VEG))
The Regents of The University of California

US Patent
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50:  325nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50250009(CHEMBL4096137 | US11208411, Compound FUR)
Affinity DataIC50: >1.00E+4nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent