BDBM50251204 CHEMBL4075591

SMILES COC(=O)C1(CC1CN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccccc1

InChI Key InChIKey=XQIPLSFFYJNKFR-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50251204   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50251204(CHEMBL4075591)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50251204(CHEMBL4075591)
Affinity DataKi:  14.6nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50251204(CHEMBL4075591)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50251204(CHEMBL4075591)
Affinity DataKi:  378nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor in rat strriatum after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50251204(CHEMBL4075591)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor in rat strriatum after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50251204(CHEMBL4075591)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of [3H]-spiperone from dopamine D2 receptor in rat strriatum after 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50251204(CHEMBL4075591)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine D1 receptor in rat striatum by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50251204(CHEMBL4075591)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to dopamine D1 receptor in rat striatum by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed