BDBM50251243 CHEMBL4079007

SMILES ONC(=O)\C=C\c1ccc(CNCc2ccc3ccccc3n2)cc1

InChI Key InChIKey=ZZAHBOBPSBJKLS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50251243   

TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50251243(CHEMBL4079007)
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC6 (unknown origin) using substrate after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50251243(CHEMBL4079007)
Affinity DataIC50: 73nMAssay Description:Inhibition of HDAC1 (unknown origin) using substrate after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetHistone deacetylase (HDAC1 and HDAC2)(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50251243(CHEMBL4079007)
Affinity DataIC50: 138nMAssay Description:Inhibition of HDAC1/2 in human HeLa cell nuclear extract using COLOR DE LYS as substrate pretreated for 5 mins followed by substrate addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50251243(CHEMBL4079007)
Affinity DataIC50: 442nMAssay Description:Inhibition of HDAC8 (unknown origin) using substrate after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2019
Entry Details Article
PubMed