BDBM50251647 1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-yloxy)-pyridin-3-yl]-amide::CHEMBL516452

SMILES Clc1ncccc1Oc1ccc(NC(=O)c2c[nH]c3ccccc23)cn1

InChI Key InChIKey=SMRGPXRMTZVWME-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50251647   

Target5-hydroxytryptamine receptor 2C(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50251647(1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-...)
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]mesulergine at human cloned 5HT2C receptor expressed in CHOK1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50251647(1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-...)
Affinity DataIC50: 590nMAssay Description:Antagonist activity at human cloned 5HT2C receptor expressed in CHO cell assessed as blockade of 5-HT-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50251647(1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]ketanserin from human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50251647(1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50251647(1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LSD from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50251647(1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50251647(1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50251647(1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50251647(1H-indole-3-carboxylic acid[6-(2-chloro-pyridin-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed