BDBM50251729 6-(2-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole::CHEMBL479548

SMILES COc1ccccc1S(=O)(=O)n1c2CCNCCc2c2ccccc12

InChI Key InChIKey=PBVVAYNTOZMIGX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251729   

Target5-hydroxytryptamine receptor 2C(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251729(6-(2-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataKi:  14nMAssay Description:Inhibition of 5HT2CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251729(6-(2-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251729(6-(2-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataIC50: 162nMAssay Description:Antagonist activity at cloned human 5HT6 receptor expressed in HeLa cells assessed as production of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed