BDBM50251886 4-((2-cyano-7-(2-cyclohexylethyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)methoxy)benzoic acid::CHEMBL520445

SMILES OC(=O)c1ccc(OCc2cc3cnc(nc3n2CCC2CCCCC2)C#N)cc1

InChI Key InChIKey=HXZUIAMQFNWBQA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251886   

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50251886(4-((2-cyano-7-(2-cyclohexylethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50251886(4-((2-cyano-7-(2-cyclohexylethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50251886(4-((2-cyano-7-(2-cyclohexylethyl)-7H-pyrrolo[2,3-d...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed