BDBM50252005 2-(3-Benzoylamino-phenyl)-2-oxoethyl ethyl trithiocarbonate::CHEMBL479611

SMILES CCSC(=S)SCC(=O)c1cccc(NC(=O)c2ccccc2)c1

InChI Key InChIKey=TUVQCBOXOZAGTR-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252005   

TargetHistone deacetylase 6(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252005(2-(3-Benzoylamino-phenyl)-2-oxoethyl ethyl trithio...)
Affinity DataIC50: 65nMAssay Description:Inhibition of recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252005(2-(3-Benzoylamino-phenyl)-2-oxoethyl ethyl trithio...)
Affinity DataKi:  110nMAssay Description:Inhibition of recombinant HDAC6 expressed in HEK293 cells using variable substrate concentration by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252005(2-(3-Benzoylamino-phenyl)-2-oxoethyl ethyl trithio...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed