BDBM50252251 2-[5-(Benzylcarbamoyl-methyl)-thiophen-2-yl]-2-oxoethyl EthylTrithiocarbonate::CHEMBL479971

SMILES CCSC(=S)SCC(=O)c1ccc(CC(=O)NCc2ccccc2)s1

InChI Key InChIKey=ONFJDPCAUONRQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252251   

TargetHistone deacetylase 6(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252251(2-[5-(Benzylcarbamoyl-methyl)-thiophen-2-yl]-2-oxo...)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50252251(2-[5-(Benzylcarbamoyl-methyl)-thiophen-2-yl]-2-oxo...)
Affinity DataIC50: 762nMAssay Description:Inhibition of recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed