BDBM50252376 CHEMBL455091::Topsentiasterol sulfate E

SMILES CC(C)C1(CC[C@@H](C)[C@H]2CC[C@@]3(C)[C@@H]4C[C@H](OS([O-])(=O)=O)[C@H]5[C@@H](O)[C@H](OS([O-])(=O)=O)[C@H](C[C@]5(C)C4=CC[C@]23C)OS([O-])(=O)=O)CC1C

InChI Key InChIKey=NKLGRJLCGSYVNU-ALGPKGRHSA-K

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252376   

TargetTranscription factor p65(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50252376(CHEMBL455091 | Topsentiasterol sulfate E)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NFkappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50252376(CHEMBL455091 | Topsentiasterol sulfate E)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of PKCzeta (unknown origin) by TR-FRET based lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed