BDBM50252396 CHEMBL4077645

SMILES ONC(=O)c1ccc(CC(=O)NC2=CC(=O)c3ccccc3C2=O)cc1

InChI Key InChIKey=AKZQXYDFSUOCDA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252396   

TargetHistone deacetylase 6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252396(CHEMBL4077645)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(acetyl)-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252396(CHEMBL4077645)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human HDAC6 using Z-(Ac)Lys-AMC as substrate after 90 mins by fluorescence based micro plate assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252396(CHEMBL4077645)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human HDAC6 using Boc Lys(Ac)-AMC as substrate preincubated for 1 hr followed by substrate addition and measured after 2 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed