BDBM50252425 CHEMBL4076052

SMILES Oc1ccc2[nH]c-3c(CCn4c-3nc3ccccc3c4=O)c2c1

InChI Key InChIKey=OLMHRSLUDJARDO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252425   

TargetCytochrome P450 1B1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50252425(CHEMBL4076052)
Affinity DataIC50: 90nMAssay Description:Inhibition of human liver microsomes CYP1B1 expressed in Escherichia coli DH5alpha coexpressing NADPH-P450 reductase using 7-ethoxyresorufin O-deethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50252425(CHEMBL4076052)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of recombinant CYP1A1 (unknown origin) expressed in Escherichia coli DH5alphaF'Iq coexpressing human NADPH-P450 reductase using E2-d4 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50252425(CHEMBL4076052)
Affinity DataIC50: 2.57E+3nMAssay Description:Inhibition of human liver microsomes CYP1A2 expressed in Escherichia coli DH5alpha coexpressing NADPH-P450 reductase using 7-ethoxyresorufin O-deethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed