BDBM50252489 2-(3-methyl-2-(3-(trifluoromethyl)phenylamino)butanoyl)piperazine-1-carbonitrile::CHEMBL521987

SMILES CC(C)C(Nc1cccc(c1)C(F)(F)F)C(=O)N1CCCCN1C#N

InChI Key InChIKey=MANOSMRLHJERON-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252489   

TargetCathepsin B(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50252489(2-(3-methyl-2-(3-(trifluoromethyl)phenylamino)buta...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50252489(2-(3-methyl-2-(3-(trifluoromethyl)phenylamino)buta...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50252489(2-(3-methyl-2-(3-(trifluoromethyl)phenylamino)buta...)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed