BDBM50252501 6-(4-chlorobenzyl)-7-(4,4-dimethylpentyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile::CHEMBL492632

SMILES CC(C)(C)CCCn1c(Cc2ccc(Cl)cc2)cc2cnc(nc12)C#N

InChI Key InChIKey=PHDAPWSITYILFC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252501   

TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252501(6-(4-chlorobenzyl)-7-(4,4-dimethylpentyl)-7H-pyrro...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252501(6-(4-chlorobenzyl)-7-(4,4-dimethylpentyl)-7H-pyrro...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252501(6-(4-chlorobenzyl)-7-(4,4-dimethylpentyl)-7H-pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed