BDBM50252522 2-(2-(3-cyanophenylamino)-3-methylbutanoyl)piperazine-1-carbonitrile::CHEMBL502439

SMILES CC(C)C(Nc1cccc(c1)C#N)C(=O)N1CCCCN1C#N

InChI Key InChIKey=VCOJPMHZVSQSKW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252522   

TargetCathepsin K(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50252522(2-(2-(3-cyanophenylamino)-3-methylbutanoyl)piperaz...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin B(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50252522(2-(2-(3-cyanophenylamino)-3-methylbutanoyl)piperaz...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50252522(2-(2-(3-cyanophenylamino)-3-methylbutanoyl)piperaz...)
Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed