BDBM50252547 6-(4-chlorobenzyl)-7-(4-chlorophenethyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile::CHEMBL521700

SMILES Clc1ccc(CCn2c(Cc3ccc(Cl)cc3)cc3cnc(nc23)C#N)cc1

InChI Key InChIKey=BJARUCXSUFPSCE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252547   

TargetCathepsin S(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252547(6-(4-chlorobenzyl)-7-(4-chlorophenethyl)-7H-pyrrol...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant cathepsin S by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252547(6-(4-chlorobenzyl)-7-(4-chlorophenethyl)-7H-pyrrol...)
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCathepsin K(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50252547(6-(4-chlorobenzyl)-7-(4-chlorophenethyl)-7H-pyrrol...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin K by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed