BDBM50252778 CHEMBL494272::N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phthalazinyl)-benzamide

SMILES Cc1ccc(cc1-c1ccc2c(nncc2c1)N1CCOCC1)C(=O)NC1CC1

InChI Key InChIKey=OZELIFLDRWQKKG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50252778   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 529nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 3.81E+3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 9.69E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252778(N-Cyclopropyl-4-methyl-3-(1-(4-morpholino)-6-phtha...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed