BDBM50252988 CHEMBL4082466

SMILES Nc1ccccc1NC(=O)c1ccc(NC(=O)CCN2C(=O)C3(OCCCO3)c3cc(Cl)ccc23)cc1

InChI Key InChIKey=ZXTYSFIDIZTHSM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252988   

TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50252988(CHEMBL4082466)
Affinity DataIC50: 32nMAssay Description:Inhibition of HDAC1 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition measured after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50252988(CHEMBL4082466)
Affinity DataIC50: 256nMAssay Description:Inhibition of HDAC2 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition measured after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50252988(CHEMBL4082466)
Affinity DataIC50: 311nMAssay Description:Inhibition of HDAC3 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition measured after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed