BDBM50253054 (S)-1-(4-Methanesulfonamidophenoxy)-3-(N-isobutyl-3,4dichlorophenylethylamino)-2-propanol::CHEMBL494105

SMILES CC(C)CN(CCc1ccc(c(c1)Cl)Cl)C[C@@H](COc2ccc(cc2)NS(=O)(=O)C)O

InChI Key InChIKey=ZAAZVMJLSXMDHB-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253054   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50253054((S)-1-(4-Methanesulfonamidophenoxy)-3-(N-isobutyl-...)
Affinity DataIC50: 370nMAssay Description:Inhibition of rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of glutamate and glycine-induced evoked current b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50253054((S)-1-(4-Methanesulfonamidophenoxy)-3-(N-isobutyl-...)
Affinity DataIC50: 730nMAssay Description:Displacement of [3H]astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed