BDBM50253139 CHEMBL4096314

SMILES [H][C@]12CN(C3CCC4(O1)C1Cc5ccc(O)cc5C4(CCN1CCc1ccccc1)C23)C(=O)c1ccccc1

InChI Key

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50253139   

TargetDelta-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50253139(CHEMBL4096314)
Affinity DataKi:  0.458nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50253139(CHEMBL4096314)
Affinity DataKi:  0.548nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50253139(CHEMBL4096314)
Affinity DataEC50:  0.610nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50253139(CHEMBL4096314)
Affinity DataEC50:  5.30nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by Eu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50253139(CHEMBL4096314)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50253139(CHEMBL4096314)
Affinity DataEC50:  404nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2019
Entry Details Article
PubMed