BDBM50253616 CHEMBL493276::endo-8-(Benzothien-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol

SMILES OC1(CC2CCC(C1)N2Cc1csc2ccccc12)c1ccc(Cl)cc1

InChI Key

Data  7 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50253616   

TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253616(endo-8-(Benzothien-3-ylmethyl)-3-(4-chlorophenyl)-...)
Affinity DataKi:  3.62nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253616(endo-8-(Benzothien-3-ylmethyl)-3-(4-chlorophenyl)-...)
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253616(endo-8-(Benzothien-3-ylmethyl)-3-(4-chlorophenyl)-...)
Affinity DataKi:  12.9nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253616(endo-8-(Benzothien-3-ylmethyl)-3-(4-chlorophenyl)-...)
Affinity DataIC50: 26.2nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253616(endo-8-(Benzothien-3-ylmethyl)-3-(4-chlorophenyl)-...)
Affinity DataKi:  70.1nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253616(endo-8-(Benzothien-3-ylmethyl)-3-(4-chlorophenyl)-...)
Affinity DataKi:  140nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253616(endo-8-(Benzothien-3-ylmethyl)-3-(4-chlorophenyl)-...)
Affinity DataKi:  1.72E+3nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253616(endo-8-(Benzothien-3-ylmethyl)-3-(4-chlorophenyl)-...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253616(endo-8-(Benzothien-3-ylmethyl)-3-(4-chlorophenyl)-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed