BDBM50253619 CHEMBL493278::endo-8-(Benzofur-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol

SMILES OC1(CC2CCC(C1)N2Cc1coc2ccccc12)c1ccc(Cl)cc1

InChI Key InChIKey=CNNRPXDUHKLPGW-UHFFFAOYSA-N

Data  7 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50253619   

TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253619(CHEMBL493278 | endo-8-(Benzofur-3-ylmethyl)-3-(4-c...)
Affinity DataKi:  0.710nMAssay Description:Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253619(CHEMBL493278 | endo-8-(Benzofur-3-ylmethyl)-3-(4-c...)
Affinity DataKi:  1.06nMAssay Description:Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253619(CHEMBL493278 | endo-8-(Benzofur-3-ylmethyl)-3-(4-c...)
Affinity DataKi:  171nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253619(CHEMBL493278 | endo-8-(Benzofur-3-ylmethyl)-3-(4-c...)
Affinity DataKi:  195nMAssay Description:Displacement of [125I]IABN from human dopamine D4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253619(CHEMBL493278 | endo-8-(Benzofur-3-ylmethyl)-3-(4-c...)
Affinity DataKi:  1.78E+3nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253619(CHEMBL493278 | endo-8-(Benzofur-3-ylmethyl)-3-(4-c...)
Affinity DataKi:  3.93E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253619(CHEMBL493278 | endo-8-(Benzofur-3-ylmethyl)-3-(4-c...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]mesulergine from 5HT2C receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253619(CHEMBL493278 | endo-8-(Benzofur-3-ylmethyl)-3-(4-c...)
Affinity DataIC50:  1.92nMAssay Description:Antagonist activity at dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuses

Curated by ChEMBL
LigandPNGBDBM50253619(CHEMBL493278 | endo-8-(Benzofur-3-ylmethyl)-3-(4-c...)
Affinity DataIC50:  0.850nMAssay Description:Antagonist activity at dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed