BDBM50253743 1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-(methylamino)-3-(naphthalen-2-yl)-1-oxopropan-2-yl)-2-propylpiperazin-1-yl)-1-oxopropan-2-yl)cyclobutanecarboxamide::CHEMBL447117

SMILES CCC[C@@H]1N(CCN([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)C1=O)C(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)C1(N)CCC1

InChI Key InChIKey=DUSMRMPLECSLRG-NGDRWEMDSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50253743   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253743(1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-...)
Affinity DataKi:  11nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253743(1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-...)
Affinity DataKi:  144nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253743(1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-...)
Affinity DataKi:  377nMAssay Description:Displacement of europium-labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253743(1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-...)
Affinity DataEC50:  84nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253743(1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-...)
Affinity DataEC50:  48nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50253743(1-Amino-N-((R)-3-(4-fluorophenyl)-1-((S)-4-((S)-1-...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed