BDBM50253885 CHEMBL4085339

SMILES ONC(=O)CCCCCCOc1ccccc1C(=O)Nc1ncnc2[nH]cnc12

InChI Key InChIKey=ORNKVDXXKWHXNG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50253885   

TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253885(CHEMBL4085339)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged BRD4 bromodomain 1 (49 to 170 residues) expressed in Escherichia coli using biotinylated peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed
TargetPeregrin(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50253885(CHEMBL4085339)
Affinity DataIC50: 2.70E+3nMAssay Description:Binding affinity to BRPF1 (unknown origin) by Isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253885(CHEMBL4085339)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50253885(CHEMBL4085339)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of BRD4 in human HL60 cells assessed as reduction in C-myc production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2019
Entry Details Article
PubMed