BDBM50254071 (S)-3-(1H-indol-4-yl)-N-methyl-3-(thiophen-2-yl)propan-1-amine hydrochloride::CHEMBL468914

SMILES CNCC[C@H](c1cccs1)c1cccc2[nH]ccc12

InChI Key InChIKey=YQKYZMKIRHBJGF-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254071   

TargetTransporter(Rat)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254071((S)-3-(1H-indol-4-yl)-N-methyl-3-(thiophen-2-yl)pr...)
Affinity DataKi:  13.8nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254071((S)-3-(1H-indol-4-yl)-N-methyl-3-(thiophen-2-yl)pr...)
Affinity DataKi:  31.9nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-dawley rat frontal cortex by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254071((S)-3-(1H-indol-4-yl)-N-methyl-3-(thiophen-2-yl)pr...)
Affinity DataIC50: 292nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed