BDBM50254073 (S)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)butan-1-amine hydrochloride::CHEMBL468915

SMILES CNCCC[C@H](c1cccs1)c1cccc2[nH]ccc12

InChI Key InChIKey=TYMPWFMJMZBIIE-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254073   

TargetTransporter(Rat)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254073((S)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254073((S)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...)
Affinity DataKi:  72.9nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-dawley rat frontal cortex by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50254073((S)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...)
Affinity DataIC50: 318nMAssay Description:Displacement of [125I]RTI55 from DAT in Sprague-dawley rat striatum by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed