BDBM50254120 CHEMBL4076681

SMILES [H][C@]12CN(C3CCC4(C1)C1Cc5ccc(O)cc5C4(CCN1CC1CC1)C23)C(=O)Oc1ccccc1

InChI Key

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50254120   

TargetKappa-type opioid receptor(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50254120(CHEMBL4076681)
Affinity DataKi:  0.522nMAssay Description:Displacement of [3H]U-69,593 from human recombinant KOR expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2019
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50254120(CHEMBL4076681)
Affinity DataKi:  0.826nMAssay Description:Displacement of [3H]DAMGO from human recombinant MOR expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50254120(CHEMBL4076681)
Affinity DataKi:  0.833nMAssay Description:Displacement of [3H]DPDPE from human recombinant DOR expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2019
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50254120(CHEMBL4076681)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human recombinant DOR expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2019
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50254120(CHEMBL4076681)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human recombinant KOR expressed in CHO cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2019
Entry Details Article
PubMed