BDBM50254349 3-(5-Amino-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-ylmethyl)-N-isopropylbenzamide::CHEMBL460596

SMILES CC(C)NC(=O)c1cccc(Cn2nnc3c(nc(N)nc23)-c2ccco2)c1

InChI Key InChIKey=GZOISEYFUNQIGG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254349   

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254349(3-(5-Amino-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]py...)
Affinity DataKi:  10.8nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254349(3-(5-Amino-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]py...)
Affinity DataKi:  530nMAssay Description:Displacement of radioligand from human recombinant adenosine A3 receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254349(3-(5-Amino-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]py...)
Affinity DataKi:  593nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254349(3-(5-Amino-7-(2-furyl)-3H-[1,2,3]triazolo[4,5-d]py...)
Affinity DataKi:  733nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed