BDBM50254399 7-(2-Furyl)-3-(5-indazolylmethyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine::CHEMBL512812

SMILES Nc1nc(-c2ccco2)c2nnn(Cc3ccc4[nH]ncc4c3)c2n1

InChI Key InChIKey=YDOSDBSTLFYMFG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50254399   

TargetAdenosine receptor A2a(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254399(7-(2-Furyl)-3-(5-indazolylmethyl)-3H-[1,2,3]triazo...)
Affinity DataKi:  8.60nMAssay Description:Displacement of radioligand from human recombinant adenosine A2A receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254399(7-(2-Furyl)-3-(5-indazolylmethyl)-3H-[1,2,3]triazo...)
Affinity DataKi:  190nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254399(7-(2-Furyl)-3-(5-indazolylmethyl)-3H-[1,2,3]triazo...)
Affinity DataKi:  206nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Vernalis R&D

Curated by ChEMBL
LigandPNGBDBM50254399(7-(2-Furyl)-3-(5-indazolylmethyl)-3H-[1,2,3]triazo...)
Affinity DataKi:  2.43E+3nMAssay Description:Displacement of radioligand from human recombinant adenosine A3 receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed